The uncomfortable truth: Most wearable data is interesting but not actionable. The metrics that actually predict mortality — VO2 max, ApoB, fasting insulin, blood pressure, body composition — require lab tests, not wrist sensors. Wearables excel at three things: sleep tracking, activity motivation, and trend detection. Buy for those reasons, not for medical-grade data.
| Test / Provider | Method | Cost | What It Measures | Accuracy | Actionability | Our Take |
|---|---|---|---|---|---|---|
| TruDiagnostic TruAge | DNA methylation (blood) | $229–$499 | DunedinPACE, GrimAge, Horvath, PhenoAge — multiple clocks | The most comprehensive option. Multiple clocks give different perspectives. DunedinPACE (pace of aging) is the most actionable metric. Best value for serious tracking. | ||
| Elysium Index | DNA methylation (blood) | $299 | Custom Elysium clock (based on Horvath lab research) | Solid science (Horvath collaboration) but only one clock. Less comprehensive than TruDiagnostic for the price. | ||
| GlycanAge | IgG glycosylation (blood) | $295–$495 | Biological age via glycan patterns on immunoglobulins | Measures a different dimension than DNA methylation (immune/inflammatory aging). Responds faster to lifestyle changes (3-6 months). Good complement to epigenetic testing. | ||
| NOVOS Age (via app) | Survey-based (no blood) | Free | Estimated biological age from lifestyle questionnaire | Free is the upside. But survey-based estimation is fundamentally less accurate than molecular measurement. Good starting point but not a substitute for blood-based testing. Our Bio Age Calculator offers similar utility for free. | ||
| Longevity Advice Calculator | Survey-based (no blood) | Free | Estimated biological age from health inputs | Free and web-based. Similar limitations to all survey-based tools — useful for motivation but not precision measurement. | ||
| IQ Healthspan Bio Age Calculator | Survey-based (no blood) | Free | Unvalidated lifestyle estimate, plus a PhenoAge calculator for nine routine blood tests | Free, no download, domain-specific breakdown shows WHERE you're aging fastest. Best free option for identifying actionable gaps. Pairs with our full tool suite. |
Our recommendation: Start with our free Bio Age Calculator to identify your weakest domains. If you want molecular-level data, TruDiagnostic's TruAge is the best value — request DunedinPACE specifically, as it measures your pace of aging (most actionable). Test twice, 6-12 months apart, to measure trajectory change rather than relying on a single data point.
| Service | Cost | Includes | Physician Access | DIY Alternative |
|---|---|---|---|---|
| Function Health | $499/yr | 100+ biomarkers, 2x/year draws, dashboard | No (interpretation only) | Use our Blood Panel Builder + Quest/LabCorp self-order (~$300-400/yr for equivalent panel) |
| InsideTracker | $189–$589/test | 5-43 biomarkers, AI recommendations, InnerAge | No | Blood Panel Builder + Lab Interpreter provides similar analysis free. Self-order through Quest for the biomarkers. |
| Blueprint Biomarkers | $499/yr | 60+ biomarkers, biological age tracking, AI | No | Similar to Function Health. Our Bio Age Calculator + Blood Panel Builder covers most of the value. |
| Healthspan (getHealthspan) | $149+/consult | Telehealth consults, prescriptions (rapamycin, metformin, NAD+) | Yes — physician prescribing | No DIY alternative for prescriptions. Legitimate if you want longevity pharmaceuticals. Worth the cost for medical guidance. |
| Peter Attia's Early Medical | $150K+/yr | Comprehensive diagnostics, personalized protocols, 1:1 physician | Yes — concierge medicine | You can replicate 70-80% of the testing and protocol design with IQH tools for <1% of the cost. The 20-30% you can't replicate is the personalized physician relationship. |
| Quest/LabCorp Direct | $25–$500/panel | Individual tests, self-order in most states | No | This IS the DIY option. Use our Blood Panel Builder to select tests, then self-order. Lab Interpreter for analysis. Best value per dollar. |
The honest bottom line: For 80% of people, self-ordering through Quest/LabCorp using our Blood Panel Builder + Lab Interpreter provides 90% of the value of premium testing services at 20% of the cost. The remaining 10% — personalized physician interpretation and prescription access — is worth paying for if you have specific health conditions or want longevity pharmaceuticals (rapamycin, metformin).