Category

Research and Clinics

24 evidence-based articles

Longevity science is advancing rapidly — new clinical trial data, novel compounds, and updated frameworks emerge every month. But the gap between what the research shows and what reaches the public through media headlines and social media is enormous. Press releases routinely overstate findings, and the supplement industry amplifies preliminary data while ignoring negative replication studies.

This category serves as your filter for the longevity research landscape. We cover the landmark clinical trials (TAME, CALERIE, Dog Aging Project), evaluate the evidence behind prominent longevity frameworks (Peter Attia's Medicine 3.0, Bryan Johnson's Blueprint), assess longevity clinics and what they actually offer versus what the science supports, and review the pharmacological frontier — rapamycin, metformin, senolytics, and partial reprogramming. We also publish protocol guides for different life stages, budgets, and health conditions, translating the research into practical frameworks you can discuss with your physician.

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The Wire
Latest longevity research news
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Personalized longevity protocol in 7 questions
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Protocol Showdown
Evidence-scored head-to-head protocol matchups
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The Longevity Mindset: Purpose, Meaning, and the Biology of Why You Wake Up
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The Top 10 Anti-Aging Claims That Science Has Debunked
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Longevity by Decade: The Right Interventions at the Right Time of Life
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The Future of Longevity Medicine: What the Next 20 Years Will Bring
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Start Here: Your Guided Reading Path
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Blue Zones: What the World's Longest-Lived Populations Actually Have in Common
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The State of Longevity Science in 2025: What We Know, What We Are Testing, and W
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Bryan Johnson's Blueprint: What It Gets Right, What the Evidence Shows, and What
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Peter Attia's Medicine 3.0: The Evidence Behind the Longevity Framework
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Social Connection and Longevity: The Biology of Belonging
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Cancer Screening for Longevity: The Evidence-Based Guide to What to Get and When
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Longevity Clinics: What They Offer, What the Evidence Supports, and What to Ask
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Air Quality and Longevity: The Invisible Environmental Factor Shortening Your Li
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The Evidence-Based Longevity Protocol: A Practical Framework for Applying Everyt
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Oral Health and Longevity: The Systemic Consequences of What Happens in Your Mou
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Longevity Genomics: What Your Genes Do and Do Not Determine About Your Lifespan
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Centenarian Biology: What People Who Live to 100 Actually Have in Common
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Skin Aging and Longevity: What Your Skin Reveals About Your Biological Age
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Psychedelic Medicine and Longevity: What the Emerging Research Actually Shows
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Is Hyperbaric Oxygen Worth the Cost? What the Evidence Shows
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Longevity for Women: The Evidence-Based Guide to the Female-Specific Aging Timel
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Longevity for Men: The Male-Specific Aging Timeline and What to Do About It
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Healthy Aging at 70 and Beyond: The Evidence-Based Guide to the Later Decades
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Cold Exposure and Longevity: Ice Baths, Cold Showers, and What the Science Actually Supports What the Science Shows
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Do Exosomes Work
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GLP-1 Agonists and Longevity: Semaglutide, Tirzepatide, Retatrutide, and the New Era of Metabolic Longevity Drugs The Honest Evidence Review
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Do Longevity Supplements
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Do Peptides Like BPC-157
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Does Fasting Actually Slow Aging? The Nuanced Truth
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Does Grounding/Earthing Have Any Evidence? The Honest Review
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NMN vs. NR: The NAD+ Precursor Battle — What the Latest Human Trials Actually Show The Honest Evidence Review
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Biological Age Testing: Which Epigenetic Clocks Are Worth Using Comparing the Clocks
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Is Methylene Blue the Next Longevity Drug? The Evidence Review
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Is Rapamycin Safe for Healthy Humans? What the Trials Show
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Is Red Light Therapy Evidence-Based? The Honest Review
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Longevity Practitioner Comparison: What Services Offer vs. What You Can Do Yourself
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Protocol Comparison Tool
Compare Attia, Johnson, and more
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Biomarkers and Testing (16) Brain and Cognition (8) Cellular and Mitochondrial Health (8) Epigenetics and Aging (10) Exercise and Performance (10) Hormones and Peptides (4) Longevity Supplements (13) Nutrition and Fasting (17) Sleep and Circadian Biology (7)
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