Epigenetics has transformed our understanding of aging from a passive, inevitable process to one that is measurable, modifiable, and potentially reversible. Epigenetic clocks — algorithms that read methylation patterns across your genome — can now estimate your biological age with remarkable accuracy, and emerging research suggests these clocks don't just measure aging but may reflect a causal driver of it.
This category covers the epigenetic dimension of aging: how DNA methylation patterns change over time, which epigenetic clocks are most predictive (GrimAge, PhenoAge, DunedinPACE), what lifestyle interventions demonstrably reverse epigenetic age, and the frontier research into partial cellular reprogramming using Yamanaka factors. We also cover telomere biology — one of the original hallmarks of aging — and the practical question of whether telomere length testing is worth the investment for individual health optimization.