Longevity Clinical Trial Tracker

Method, limits and how to read your result

How it works

We search the ClinicalTrials.gov registry for interventions studied for aging (rapamycin, metformin, senolytics, NAD+ precursors, calorie restriction and others) and keep trials whose title, conditions or keywords mention aging-related concepts. Status, phase, enrollment and sponsor come straight from the registry. Featured trials add a plain-language summary; where results are published, the summary states only what the paper's abstract reports, such as the PEARL rapamycin trial, whose primary outcome did not change (PEARL).

Limits

Registry entries are maintained by trial sponsors and can be out of date; "status unknown" means the sponsor has not updated the record. A keyword search will miss some relevant trials and include some that are only loosely related. Listing a trial is not an endorsement, and "results posted" means results exist on the registry, not that they were positive. Some well-known efforts are not registered at all: TAME, the proposed trial of metformin to target aging (Barzilai 2016), had no ClinicalTrials.gov record as of 2026-10-03.

How to read your result

Use the status filter to find trials listed as recruiting, and open the registry link for eligibility, locations and contacts. A completed trial with results posted is the place to look for what an intervention actually did; small or open-label trials are early steps, not proof of benefit.