Category

Brain and Cognition

8 evidence-based articles

Cognitive decline is not an inevitable consequence of aging — it is a process that begins decades before symptoms appear and is substantially modifiable through targeted intervention. The brain consumes 20% of the body's energy despite representing only 2% of its mass, making it uniquely vulnerable to metabolic dysfunction, inflammation, and vascular damage.

This category covers the neuroscience of aging and cognitive preservation. From BDNF — the neurotrophin most responsive to exercise — to the gut-brain axis and its role in neuroinflammation, each article translates peer-reviewed neuroscience into actionable strategies. We cover Alzheimer's prevention (starting decades before diagnosis), the role of sleep in amyloid clearance, how specific exercise modalities protect different cognitive domains, and which supplements have credible evidence for neuroprotection. The goal is not just avoiding dementia — it is maintaining peak cognitive performance across the entire lifespan.

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Biological Age Calculator
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Supplement Evidence Database
Evidence grades for nootropics and neuroprotective compounds
Neuroplasticity Across the Lifespan: How the Brain Rewires Itself and What Drive
Alzheimer's Prevention: The Evidence-Based Case for Aggressive Early Action Star
The Brain Longevity Blueprint: How to Protect Your Cognitive Health for Life
BDNF: The Brain Growth Factor That Exercise, Sleep, and Diet All Activate
Chronic Stress, Cortisol, and Aging: The Longevity Cost of Always Being On
Depression, Mental Health, and Longevity: The Biological Link Between Mood and L
Parkinson's Disease Prevention: What the Evidence Shows About Reducing Your Risk
Exercise and the Brain: The Neurobiological Case for Moving Your Body
Longevity Protocol with ADHD: Medication Interactions, Dopamine, and Evidence-Based Str...
Longevity Protocol with Anxiety & Depression: SSRI Interactions, Cortisol, and Evidence...
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Biomarkers and Testing (16) Cellular and Mitochondrial Health (8) Epigenetics and Aging (10) Exercise and Performance (10) Hormones and Peptides (4) Longevity Supplements (13) Nutrition and Fasting (17) Research and Clinics (24) Sleep and Circadian Biology (7)
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